(Very Rough draft) Golem-to-Human: Technological Details
Alexander Ohnemus
Biotechnology
22 September 2024
Golem-to-Human: Technological Details
Table of contents:
Introduction
Phenotypic Revolutions
Potential Ectogenesis for the Deceased
In Order to Extract Reparations out of Willing Northwestern European Volunteers, Mass Ectogenesis for them.
Consenting Individuals’ Privilege Distribution(Somatic and Germinal).
Introduction
Phenotypic revolutions(when technology, that was originally designated to replicate its creator species, goes rogue and takes over its creators) either do happen or humans should keep their own fertility anyway. Humans using robots to reproduce their own human offspring is fine, so long as all parties remain capable of reproducing.
Technological details are missing from previous books of this Golem series. Replicating the phenotypes of deceased people may be impossible and not worth current resources.
YET with enough phenotypic(photos, recordings, descriptions, etc.) and genotypic(DNA of relatives, lineage DNA, ethnic DNA, populational(maybe racialized) DNA, general human genome, genealogy, etc.) data, both of a deceased person, one can either clone that dead subject(having deduced the genotype) or reproduce another human with the same traits the deceased is remembered for, plus silver lining, added genetic diversity.
Also, TO PAY REPARATIONS TO PEOPLE OF COLOR, stem cells could go through a 3D-printer to mass reproduce offspring, for currently living Northwestern European individuals, so they and their offspring can pay reparations.
MAYBE consenting adults, and their offspring, can even obtain recessive privileges. Recessive and progressive traits both correlate with a higher mutational load because they both result from mutations. Mutations, without removing individuals( examples: founder effects, bottleneck effects, etc.), actually raise both genetic and phenotypic diversity. Thus, genetically engineered somatic and germline mutations, utilizing a recessive genetic correlation, may provide more genetic and phenotypic diversity than clones.
1)Phenotypic Revolutions
Either phenotypic revolutions happen beyond a reasonable doubt, or humans should keep their own reproductive capacities anyway.
Works Cited
Ohnemus , Alexander . “PREVIEW: GCG.” ResearchGate.net , Ohnemus University , 16 Sept. 2024, www.researchgate.net/publication/384113155_PREVIEW_GCG. Accessed 22 Sept. 2024.
http://dx.doi.org/10.13140/RG.2.2.16490.73925. “Outline: Golem tradition, philosophy, science, risk analysis, skin in the game and engineering. 1)AI replicate a dead individual’s phenotype with software. 2)User change replicate phenotype to be both more progressive and recessive. 3)3D print phenotype with stem cells. 4)Allow 3D printed phenotype to reproduce itself. 5)Reparation paying life created and repeat.”
Ohnemus, Alexander . “GHCG: Golems-To-Humans for the Common Good.”ResearchGate.net. Ohnemus University , 21 Sept. 2024, www.researchgate.net/publication/384233495_GHCG_Golems-to-Humans_for_the_Common_Good. Accessed 22 Sept. 2024.
Gariépy, J.F. “The Revolutionary Phenotype: The Amazing Story of How Life Begins and How It Ends.” Amazon.com, CreateSpace Independent Publishing Platform, 4 Dec. 2018, www.amazon.com/Revolutionary-Phenotype-amazing-story-begins/dp/1729861563. Accessed 25 Sep. 2024.
“The Revolutionary Phenotype is a science book that brings us four billion years into the past, when the first living molecules showed up on Planet Earth. Unlike what was previously thought, we learn that DNA-based life did not emerge from random events in a primordial soup. Indeed, the first molecules of DNA were fabricated by a previous life form. By describing the fascinating events referred to as Phenotypic Revolutions, this book provides a dire warning to humanity: if humans continue to play with their own genes, we will be the next life form to fall to our own creation. ‘I am VERY impressed with this book—very important topic very well treated.’ - Robert Trivers.”
Alberts B, Johnson A, Lewis J, et al. “Molecular Biology of the Cell.” Ncbi.nlm.nih.gov, New York: Garland Science, 2002, www.ncbi.nlm.nih.gov/books/NBK26876/. Accessed 25 Sept. 2024.
“Go to: Summary From our knowledge of present-day organisms and the molecules they contain, it seems likely that the development of the directly autocatalytic mechanisms fundamental to living systems began with the evolution of families of molecules that could catalyze their own replication. With time, a family of cooperating RNA catalysts probably developed the ability to direct synthesis of polypeptides. DNA is likely to have been a late addition: as the accumulation of additional protein catalysts allowed more efficient and complex cells to evolve, the DNA double helix replaced RNA as a more stable molecule for storing the increased amounts of genetic information required by such cells.”
Ohnemus , Alexander . “If Phenotypic Revolutions Occurred from Proteins, to RNA and Finally DNA, Then Is Aging a Counter Phenotypic Revolution?” ResearchGate.net, Ohnemus University , 18 Aug. 2024, www.researchgate.net/post/If_phenotypic_revolutions_occurred_from_proteins_to_RNA_and_finally_DNA_then_is_aging_a_counter_phenotypic_revolution. Accessed 25 Sept. 2024.
“If phenotypic revolutions occurred from proteins, to RNA and finally DNA, then is aging a counter phenotypic revolution? Aging probably is a counter phenotypic revolution because it results from scratches on epigenome. Epigenetic information is usually carried by the suspected past rulers, RNA then proteins. References: “We do know that the previous life form used a molecule called RNA as its genetic material”(page 12). “We tend to assume they were small, because the only survivors of this previous life form are the microscopic RNA viruses, but in truth, we have no idea”(page 12). “In addition to the few RNA viruses that were left alive, DNA seems to have recycled the RNA molecules into tools that cannot reproduce on their own. In other words, DNA literally sterilized RNA and put it to good use. And we too will be sterilized if we refuse to learn from these past events”( page 12). “The information transfers that occur between DNA, RNA and proteins during the production of new proteins are referred to as the “dogma of biology.” Each of these molecules is converted into the molecule of the next step according to what we call the genetic code”( page 13). ‘The Revolutionary Phenotype: The Amazing Story of How Life Begins and How It Ends: Gariépy, J. -F., Éditions, Élora: 9781729861561: Amazon.com: Books.” A.co, December 7, 2018, a.co/d/bAS26cI. Accessed 18 Aug. 2024. Me: https://www.researchgate.net/publication/382330574_Deducing_ITOA’s_Veracity.”.
Ohnemus , Alexander . “Information Theory of Abiogenesis.” ResearchGate.net, Ohnemus University , 21 Sept. 2024, www.researchgate.net/publication/384232018_Information_Theory_of_Abiogenesis?channel=doi&linkId=66ef1fbf19c9496b1fb51eb7&showFulltext=true. Accessed 25 Sept. 2024. “ Information Theory of Abiogenesis: Life’s origin is a mystery. Science may never note for sure how life originated. However, engineering MAY create life. Then one MAY deduce information theory(more specifically creating a phenotype, then a corresponding replicator) is at least how certain life was created.”
Ohnemus , Alexander . “ANTI-Racist Optimization between “Dysgenics” and “Phenotypic Revolutions.”” ResearchGate.net, Ohnemus University , 20 Aug. 2024, www.researchgate.net/publication/383264790_ANTI-Racist_Optimization_Between_Dysgenics_and_Phenotypic_Revolutions. Accessed 25 Sept. 2024. “ GIVEN AN INDIVIDUAL’S DNA SIGNATURE REMAINS AFTER ANY AMOUNT OF GENETIC ENGINEERING: The optimal birth rate, and method, lies between dysgenic civilizational collapse and phenotypic revolution. Dysgenics result from not enough genetic engineering. Phenotypic revolutions derive from excessive genetic engineering. Optimal birth rate: In words: Between phenotypic revolution and other dysgenic collapse. Excluding both tail risks of phenotypic revolution and other dysgenic collapse. Interval form: (Phenotypic Revolution, dysgenic collapse) Optimal genetic engineering: In words: Between phenotypic revolution and other dysgenic collapse. Excluding both tail risks of phenotypic revolution and other dysgenic collapse. Interval form: (Phenotypic revolution, dysgenic collapse).”
Ohnemus , Alexander . “"AARRR"ANTI-Racist Anthology: Reparations PAID by Recessive Reproduction.” ResearchGate.net , Ohnemus University , 29 Aug. 2024, www.researchgate.net/publication/383524095_AARRRANTI-racist_Anthology_Reparations_PAID_BY_Recessive_Reproduction?channel=doi&linkId=66d0b4ddb1606e24c2a87541&showFulltext=true. Accessed 25 Sept. 2024. “ Maybe humans, through mass automation, COULD mass reproduce fellow homo sapiens with recessive alleles(such as ANTI-racism, liberalism, democracy, progressivism, creativity, intelligence and the other recessive traits and genes minus the diseases), without cloning per se. Epigenetic information polish could remove recessive diseases. Aiming for the recessive would also mitigate a phenotypic revolution. Recessive ≠ useful to machines. “Artificial wombs(robots birthing humans) may still mitigate phenotypic revolutions, so long as the machine itself doesn’t reproduce and only human DNA does. Plus, maybe one could create a human egg from human somatic cells. The issues will hopefully work out.”
UPM BIOMEDICALS. “What Is 3D Bioprinting?” Upmbiomedicals.com, UPM BIOMEDICALS, www.upmbiomedicals.com/solutions/life-science/what-is-3d-bioprinting/. Accessed 22 Sept. 2024.
“3D bioprinting is an additive manufacturing process that uses bioinks to print living cells developing structures layer-by-layer which imitate the behavior and structures of natural tissues.” “3D Bioprinting solutions – hints and tips for bioprinting 1)Select the most suitable bioink for your research purpose and ensure the bioink you are using is compatible with the selected printing method and cell types 2)Know what you are printing – create a new digital 3D model of the structure you want to print or get a license for an existing model 3)Use fresh or new printer tips that are specifically fitted for your system 4)Test different nozzle/needle sizes, printing speeds, and layer heights and optimize them based on the results 5)Make sure the working temperature is suitable for the printer and the used materials 6)Set an optimal printing pressure. A bit higher pressure is usually needed when printing with cells.”
CELLINK. “What Is a Bioink?” Cellink.com, www.cellink.com/what-is-bioink/. Accessed 22 Sept. 2024. “A bioink is any natural or synthetic polymer which has been selected for its biocompatible components and favorable rheological properties. A bioink will typically support living cells, and its characteristics aids cell adhesion, cell proliferation and cell differentiation during maturation.”
Britannica, The Editors of Encyclopaedia. "polymer". Encyclopedia Britannica, 16 Sep. 2024, https://www.britannica.com/science/polymer. Accessed 22 September 2024. “A polymer is any of a class of natural or synthetic substances composed of very large molecules, called macromolecules, which are multiples of simpler chemical units called monomers. Polymers make up many of the materials in living organisms and are the basis of many minerals and man-made materials.”
“Rheological Properties.” Link.springer.com, Springer, Berlin, Heidelberg, 2007, link.springer.com/chapter/10.1007/978-3-540-34194-9_4. Accessed 22 Sept. 2024. “Rheology is the branch of physics in which we study the way in which materials deform or flowin response to applied forces or stresses. The material properties that govern the specific way in which these deformation or flow behaviors occur are called rheological properties.”
Aufieri, Roberto, et al. “3D Printing in Neonatal Care.” Ncbi.nlm.nih.gov, 24 Sept. 2015, www.ncbi.nlm.nih.gov/pmc/articles/PMC4595382/. Accessed 22 Sept. 2024.
“Only a few experiences have instead been reported in newborn and infants. 3D printed individualized bioresorbable airway splints have been used for the treatment of three infants with severe tracheobronchomalacia, ensuring resolution of pulmonary and extrapulmonary symptoms [6,7]. A 3D model of a complex congenital heart defects have been used for preoperative planning of intraoperative procedures, allowing surgeons to repair a complex defect in a single intervention [8]. As already shown for children with obstructive sleep apnea and craniofacial anomalies [9]. personalized 3D printed masks could improve CPAP effectiveness and comfort also in term and preterm neonates. Neonatal emergency transport services and rural hospitals could also benefit from this technology, making possible to print medical devices spare parts, surgical and medical instruments wherever not readily available. It is envisaged that 3D printing, in the next future, will give its contribute toward the individualization of neonatal care, although further multidisciplinary studies are still needed to evaluate safety, possible applications and realize its full potential.”